...It is a severe supportive form of acne, characterized by presence of comedones, nodules and cysts with burrowing abscesses and irregular scarring. The lesions are situated chiefly on the back, chest, shoulders and buttocks....»
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«...Inflammation Is the Result of a Multi-faceted ProcessHormonal changes are at the root of acne pathogenesis.The primary target of acne is the pilosebaceous unit of the follicle.Hormones stimulate increased production of lipids in the follicle.Inflammation probably arises from the presence of prostaglandins and cytokines that are attracted to the lipids within the follicle.Some individuals may be genetically prone to overactive inflammatory pathways, which increases their chances of having severe inflammatory acne....»
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